4:05 p.m. ET | Fox
Matchup rating: 79.4 | Spread: LAR -3 (48)
What to watch for: It'll be known early in the game just how much Cardinals quarterback Kyler Murray's right shoulder has improved. If he starts running early, then it's better. If he doesn't, then it's still an issue. Coach Kliff Kingsbury won't run Murray on designed calls if there's a chance of him getting hit and hurt more. But whether Murray runs will have a distinct impact and could be the difference between Arizona winning -- or losing for the fourth time in five games. -- Josh Weinfuss
Bold prediction: Rookie Rams running back Cam Akers will tally his first 100-rushing-yard game. The Rams have not been able to get their running game going since Week 10, but against a Cardinals defense that is allowing an average of 123 yards per game, watch for coach Sean McVay to commit to it. Akers is coming off a nine-carry, 84-yard performance in Week 12. -- Lindsey Thiry
Stat to know: The Cardinals lead NFL in yards per rush (5.0), rank fourth in rushing yards per game (155.9) and sit at second in run block win rate (73%). But the Rams have allowed the fourth-fewest rushing yards per game (93.5) this season.
What to know for fantasy: Cause for concern? The Rams have been the best defense against fantasy receivers this season, and three of DeAndre Hopkins' four worst games this season have come since Arizona's Week 8 bye. See Week 13 rankings.
Betting nugget: Arizona is 12-6-1 ATS as an underdog under Kingsbury. And it's 5-3 ATS as a home underdog under Kingsbury, with all five covers also going over the total. Read more.
Thiry's pick: Rams 28, Cardinals 20
Weinfuss' pick: Cardinals 24, Rams 21
FPI prediction: LAR, 53.7% (by an average of 1.3 points)
Matchup must-reads: Rams' Goff vows to do better after loss, criticism ... Have teams cracked the code on Cardinals' Murray? ... Rams coach McVay says Goff "has got to take better care of the football" ... Cardinals first-round pick Simmons finding "the flow of it"
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December 06, 2020 at 01:02PM
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How much will Cardinals' Kyler Murray run against the Rams? - Arizona Cardinals Blog- ESPN - ESPN
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